| ncRNA name | Rac1 siRNA |
| ncRNA Category | siRNA |
| Disease name | diabetic retinopathy (DR) |
| Species | Rattus norvegicus |
| Tissues/Cell_line | rat retinal endothelial cells (RRECs) |
| Methods | siRNA transfection, [3H]sucrose permeability assay, qPCR, Western blot |
| Expression pattern | associated |
| Functional description | Rac1 inhibition by Rac1-siRNA transfection effectively prevented hyperpermeability, β-catenin expression and the VE-cadherin expression decrease in high glucose-induced RRECs. |
| PubMed ID | 25452781 |
| Year | 2015 |
| Title | Ras-related C3 botulinum toxin substrate 1 activation is involved in the pathogenesis of diabetic retinopathy. |
| Drug-related ncRNA | NO |
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